In our organization, McAfee ePO server has been running fine until a couple of days ago. We’ve experienced a turnover in IT personnel and I have been changing different administrator names\passwords as part of security practice. After required changes done, restarted all the servers. Everything was fine except McAfee ePO web portal; I was not able to login.
It’s throwing below given errors:
DataChannel – Dependency scheduler had initialization error
LYNXSHLD1510 – dependency EPOCore had initialization error
AvertAlerts – Dependency scheduler had initialization error

All the errors were initialization errors.
SOLUTION:
Check the SQL DB connectivity with McAfee ePO; open your browser and type https://ServerName:8443/core/config
Log on with ePO credentials. (See Image-2)

Type new user name and passwords, click “Test Connection”
Click Apply, if the test is successful.
Restart your ePO server, that’s it.
Happy computing!!
Source: McAfee